Tadalafil is an orally administred drug used to treat male erectile dysfunction (impotence). Due to its 36-hour effect it is also known as the weekend pill. As with sildenafil and vardenafil, it is recommended that tandalafill be used no more than once daily.
20 mg
1
Total $ 40.00 USD
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Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, wich stimulates the synthesis of cGMP in smooth muscle cells, Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) enhances erectile function by increasing the amount of cGMP. Tadalafil (as well as sildenafil and vardenafil) inhibits PDE5. Because sexual stimulation is required to initiate the local release of nitric oxide, the inhibition of PDE5 by tadalafil has no effect in the absence or sexual stimulation. To avoid the inconvienence of men with erectile dysfunction needing to plan use of tabalaplex around anticipated sexual activity
Benefits
Erectile dysfunction treatment
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